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Accumulation of long-term transcriptionally active integrated retroviral vectors in active promoters and enhancers

Most retroviruses preferentially integrate into certain genomic locations and, as a result, their genome-wide integration patterns are non-random. We investigate the epigenetic landscape of integrated retroviral vectors and correlate it with the long-term stability of proviral transcription. Retrovi...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Šenigl, Filip, Miklík, Dalibor, Auxt, Miroslav, Hejnar, Jiří
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727404/
https://ncbi.nlm.nih.gov/pubmed/29244184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx889
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