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Proviruses with Long-Term Stable Expression Accumulate in Transcriptionally Active Chromatin Close to the Gene Regulatory Elements: Comparison of ASLV-, HIV- and MLV-Derived Vectors

Individual groups of retroviruses and retroviral vectors differ in their integration site preference and interaction with the host genome. Hence, immediately after infection genome-wide distribution of integrated proviruses is non-random. During long-term in vitro or persistent in vivo infection, th...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Miklík, Dalibor, Šenigl, Filip, Hejnar, Jiří
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869509/
https://ncbi.nlm.nih.gov/pubmed/29517993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10030116
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