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Proviruses with Long-Term Stable Expression Accumulate in Transcriptionally Active Chromatin Close to the Gene Regulatory Elements: Comparison of ASLV-, HIV- and MLV-Derived Vectors

Individual groups of retroviruses and retroviral vectors differ in their integration site preference and interaction with the host genome. Hence, immediately after infection genome-wide distribution of integrated proviruses is non-random. During long-term in vitro or persistent in vivo infection, th...

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Vydáno v:Viruses
Hlavní autoři: Miklík, Dalibor, Šenigl, Filip, Hejnar, Jiří
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869509/
https://ncbi.nlm.nih.gov/pubmed/29517993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10030116
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