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Transcriptional provirus silencing as a crosstalk of de novo DNA methylation and epigenomic features at the integration site

The autonomous transcription of integrated retroviruses strongly depends on genetic and epigenetic effects of the chromatin at the site of integration. These effects are mostly suppressive and proviral activity can be finally silenced by mechanisms, such as DNA methylation and histone modifications....

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Detalhes bibliográficos
Main Authors: Šenigl, Filip, Auxt, Miroslav, Hejnar, Jiří
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384319/
https://ncbi.nlm.nih.gov/pubmed/22379139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks197
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