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Transcriptional provirus silencing as a crosstalk of de novo DNA methylation and epigenomic features at the integration site
The autonomous transcription of integrated retroviruses strongly depends on genetic and epigenetic effects of the chromatin at the site of integration. These effects are mostly suppressive and proviral activity can be finally silenced by mechanisms, such as DNA methylation and histone modifications....
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384319/ https://ncbi.nlm.nih.gov/pubmed/22379139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks197 |
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