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Rationale for targeting the Wnt signalling modulator Dickkopf‐1 for oncology

Wnt signalling is a fundamental pathway involved in embryonic development and adult tissue homeostasis. Mutations in the pathway frequently lead to developmental defects and cancer. As such, therapeutic intervention of this pathway has generated tremendous interest. Dickkopf‐1 (DKK1) is a secreted i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Br J Pharmacol
मुख्य लेखकों: Kagey, Michael H, He, Xi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727329/
https://ncbi.nlm.nih.gov/pubmed/28574171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13894
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