Mechanism of inhibition of taurolithocholate‐induced retrieval of plasma membrane MRP2 by cyclic AMP and tauroursodeoxycholate

Taurolithocholate (TLC) produces cholestasis by inhibiting biliary solute secretion in part by retrieving MRP2 from the plasma membrane (PM). Tauroursodeoxycholate (TUDC) and cAMP reverse TLC‐induced cholestasis by inhibiting TLC‐induced retrieval of MRP2. However, cellular mechanisms for this rever...

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Bibliografiska uppgifter
I publikationen:Physiol Rep
Huvudupphovsmän: Park, Se Won, Webster, Cynthia R. L., Anwer, Mohammed S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727282/
https://ncbi.nlm.nih.gov/pubmed/29192063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13529
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