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Molecular mechanism of K65 acetylation-induced attenuation of Ubc9 and the NDSM interaction
The negatively charged amino acid-dependent sumoylation motif (NDSM) carries an additional stretch of acidic residues downstream of the consensus Ψ-K-x-E/D sumoylation motif. We have previously shown that acetylation of the SUMO E2 conjugase enzyme, Ubc9, at K65 downregulates its binding to the NDSM...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5727262/ https://ncbi.nlm.nih.gov/pubmed/29234076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17465-0 |
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