Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response

While numerous small ubiquitin-like modifier (SUMO) conjugated substrates have been identified, very little is known about the cellular signalling mechanisms that differentially regulate substrate sumoylation. Here, we show that acetylation of SUMO E2 conjugase Ubc9 selectively downregulates the sum...

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Detalhes bibliográficos
Main Authors: Hsieh, Yung-Lin, Kuo, Hong-Yi, Chang, Che-Chang, Naik, Mandar T, Liao, Pei-Hsin, Ho, Chun-Chen, Huang, Tien-Chi, Jeng, Jen-Chong, Hsu, Pang-Hung, Tsai, Ming-Daw, Huang, Tai-Huang, Shih, Hsiu-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604730/
https://ncbi.nlm.nih.gov/pubmed/23395904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.5
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