SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx

Small ubiquitin-like modifier (SUMO) modification is emerging as an important control in transcription regulation. Here, we show that CREB-binding protein (CBP), a versatile transcriptional coactivator for numerous transcription factors in response to diverse signaling events, can be modified by SUM...

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Bibliographische Detailangaben
Hauptverfasser: Kuo, Hong-Yi, Chang, Che-Chang, Jeng, Jen-Chong, Hu, Hui-Mei, Lin, Ding-Yen, Maul, Gerd G., Kwok, Roland P. S., Shih, Hsiu-Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287974/
https://ncbi.nlm.nih.gov/pubmed/16287980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504460102
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