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The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors
The lipid phosphatase Ship2 represents a drug discovery target for the treatment of different diseases, including cancer. Its C-terminal sterile alpha motif domain (Ship2-Sam) associates with the Sam domain from the EphA2 receptor (EphA2-Sam). This interaction is expected to mainly induce pro-oncoge...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5727260/ https://ncbi.nlm.nih.gov/pubmed/29234063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17684-5 |
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