Lipoteichoic acid deficiency permits normal growth but impairs virulence of Streptococcus pneumoniae

Teichoic acid (TA), a crucial cell wall constituent of the pathobiont Streptococcus pneumoniae, is bound to peptidoglycan (wall teichoic acid, WTA) or to membrane glycolipids (lipoteichoic acid, LTA). Both TA polymers share a common precursor synthesis pathway, but differ in the final transfer of th...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Heß, Nathalie, Waldow, Franziska, Kohler, Thomas P., Rohde, Manfred, Kreikemeyer, Bernd, Gómez-Mejia, Alejandro, Hain, Torsten, Schwudke, Dominik, Vollmer, Waldemar, Hammerschmidt, Sven, Gisch, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727136/
https://ncbi.nlm.nih.gov/pubmed/29233962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01720-z
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