Structural Reevaluation of Streptococcus pneumoniae Lipoteichoic Acid and New Insights into Its Immunostimulatory Potency

Streptococcus pneumoniae is a Gram-positive human pathogen with a complex lipoteichoic acid (pnLTA) structure. Because the current structural model for pnLTA shows substantial inconsistencies, we reinvestigated purified and, more importantly, O-deacylated pnLTA, which is most suitable for NMR spectr...

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Detalhes bibliográficos
Main Authors: Gisch, Nicolas, Kohler, Thomas, Ulmer, Artur J., Müthing, Johannes, Pribyl, Thomas, Fischer, Kathleen, Lindner, Buko, Hammerschmidt, Sven, Zähringer, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668725/
https://ncbi.nlm.nih.gov/pubmed/23603911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.446963
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