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Attachment of phosphorylcholine residues to pneumococcal teichoic acids and modification of substitution patterns by the phosphorylcholine esterase

The bacterial lung pathogen Streptococcus pneumoniae has a unique nutritional requirement for exogenous choline and attaches phosphorylcholine (P-Cho) residues to the GalpNAc moieties of its teichoic acids (TAs) in its cell wall. Two phosphorylcholine transferases, LicD1 and LicD2, mediate the attac...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Waldow, Franziska, Kohler, Thomas P., Hess, Nathalie, Schwudke, Dominik, Hammerschmidt, Sven, Gisch, Nicolas
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036202/
https://ncbi.nlm.nih.gov/pubmed/29764936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003360
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