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Isomerization of N-Allyl Amides to Form Geometrically Defined Di-, Tri-, and Tetrasubstituted Enamides

Enamides represent bioactive pharmacophores in various natural products, and have become increasingly common reagents for asymmetric incorporation of nitrogen functionality. Yet the synthesis of the requisite geometrically defined enamides remains problematic, especially for highly substituted and Z...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Trost, Barry M., Cregg, James J., Quach, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726938/
https://ncbi.nlm.nih.gov/pubmed/28252296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b00564
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