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Spleen Tyrosine Kinase Inhibition Modulates p53 Activity
Spleen tyrosine kinase (SYK) is a cytoplasmic enzyme that promotes survival and proliferation of B cells. SYK inhibition has shown promising results in the treatment of arthritis and chronic lymphocytic leukemia (CLL). However, in other context, it has been shown that SYK overexpression in epithelia...
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| Publicado no: | J Cell Death |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5726622/ https://ncbi.nlm.nih.gov/pubmed/29249894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1179066017731564 |
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