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Sequencing and phasing cancer mutations in lung cancers using a long-read portable sequencer
Here, we employed cDNA amplicon sequencing using a long-read portable sequencer, MinION, to characterize various types of mutations in cancer-related genes, namely, EGFR, KRAS, NRAS and NF1. For homozygous SNVs, the precision and recall rates were 87.5% and 91.3%, respectively. For previously report...
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| Pubblicato in: | DNA Res |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5726485/ https://ncbi.nlm.nih.gov/pubmed/29117310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dsx027 |
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