Adipocytes Sequester and Metabolize the Chemotherapeutic Daunorubicin

Obesity is associated with poorer outcome for many cancers. Previously, we observed that adipocytes protect acute lymphoblastic leukemia (ALL) cells from the anthracycline, daunorubicin (DNR). In the present study, it is determined whether adipocytes clear DNR from the tumor microenvironment (TME)....

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Publicat a:Mol Cancer Res
Autors principals: Sheng, Xia, Parmentier, Jean-Hugues, Tucci, Jonathan, Pei, Hua, Cortez-Toledo, Omar, Dieli-Conwright, Christina M., Oberley, Matthew J., Neely, Michael, Orgel, Etan, Louie, Stan G., Mittelman, Steven D.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726435/
https://ncbi.nlm.nih.gov/pubmed/29117945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0338
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