Adipocytes Sequester and Metabolize the Chemotherapeutic Daunorubicin

Obesity is associated with poorer outcome for many cancers. Previously, we observed that adipocytes protect acute lymphoblastic leukemia (ALL) cells from the anthracycline, daunorubicin (DNR). In the present study, it is determined whether adipocytes clear DNR from the tumor microenvironment (TME)....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cancer Res
Prif Awduron: Sheng, Xia, Parmentier, Jean-Hugues, Tucci, Jonathan, Pei, Hua, Cortez-Toledo, Omar, Dieli-Conwright, Christina M., Oberley, Matthew J., Neely, Michael, Orgel, Etan, Louie, Stan G., Mittelman, Steven D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726435/
https://ncbi.nlm.nih.gov/pubmed/29117945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0338
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