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Adipocytes Sequester and Metabolize the Chemotherapeutic Daunorubicin

Obesity is associated with poorer outcome for many cancers. Previously, we observed that adipocytes protect acute lymphoblastic leukemia (ALL) cells from the anthracycline, daunorubicin (DNR). In the present study, it is determined whether adipocytes clear DNR from the tumor microenvironment (TME)....

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發表在:Mol Cancer Res
Main Authors: Sheng, Xia, Parmentier, Jean-Hugues, Tucci, Jonathan, Pei, Hua, Cortez-Toledo, Omar, Dieli-Conwright, Christina M., Oberley, Matthew J., Neely, Michael, Orgel, Etan, Louie, Stan G., Mittelman, Steven D.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726435/
https://ncbi.nlm.nih.gov/pubmed/29117945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0338
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