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Adipocytes Sequester and Metabolize the Chemotherapeutic Daunorubicin

Obesity is associated with poorer outcome for many cancers. Previously, we observed that adipocytes protect acute lymphoblastic leukemia (ALL) cells from the anthracycline, daunorubicin (DNR). In the present study, it is determined whether adipocytes clear DNR from the tumor microenvironment (TME)....

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Publicado en:Mol Cancer Res
Autores principales: Sheng, Xia, Parmentier, Jean-Hugues, Tucci, Jonathan, Pei, Hua, Cortez-Toledo, Omar, Dieli-Conwright, Christina M., Oberley, Matthew J., Neely, Michael, Orgel, Etan, Louie, Stan G., Mittelman, Steven D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726435/
https://ncbi.nlm.nih.gov/pubmed/29117945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0338
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