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Mechanisms of μ-opioid receptor inhibition of NMDA receptor-induced substance P release in the rat spinal cord

The interaction between NMDA receptors and μ-opioid receptors in primary afferent terminals was studied by using NMDA to induce substance P release, measured as neurokinin 1 receptor internalization. In rat spinal cord slices, the μ-opioid receptor agonists morphine, DAMGO and endomorphin-2 inhibite...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuropharmacology
Prif Awduron: Chen, Wenling, Ennes, Helena S., McRoberts, James A., Marvizon, Juan Carlos
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726399/
https://ncbi.nlm.nih.gov/pubmed/29042318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.10.014
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