Targeted i.v. BU and fludarabine (t-i.v. BU/Flu) provides effective control of AML in adults with reduced toxicity

Myeloablative doses of BU and fludarabine followed by allogeneic hematopoietic cell transplantation offer effective therapy for AML. We anticipated that pharmacokinetic targeting of i.v. BU to 5300 μm/L min/day × 4 (targeted i.v. BU and fludarabine (t-i.v. BU/Flu)) would limit nonrelapse mortality (...

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Bibliografische gegevens
Gepubliceerd in:Bone Marrow Transplant
Hoofdauteurs: Pidala, J, Kim, J, Anasetti, C, Kharfan-Dabaja, MA, Field, T, Perkins, J, Ayala, E, Perez, L, Fernandez, H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726256/
https://ncbi.nlm.nih.gov/pubmed/20711242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2010.190
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