Targeted i.v. BU and fludarabine (t-i.v. BU/Flu) provides effective control of AML in adults with reduced toxicity

Myeloablative doses of BU and fludarabine followed by allogeneic hematopoietic cell transplantation offer effective therapy for AML. We anticipated that pharmacokinetic targeting of i.v. BU to 5300 μm/L min/day × 4 (targeted i.v. BU and fludarabine (t-i.v. BU/Flu)) would limit nonrelapse mortality (...

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Detalhes bibliográficos
Publicado no:Bone Marrow Transplant
Main Authors: Pidala, J, Kim, J, Anasetti, C, Kharfan-Dabaja, MA, Field, T, Perkins, J, Ayala, E, Perez, L, Fernandez, H
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726256/
https://ncbi.nlm.nih.gov/pubmed/20711242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2010.190
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