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Targeted i.v. BU and fludarabine (t-i.v. BU/Flu) provides effective control of AML in adults with reduced toxicity

Myeloablative doses of BU and fludarabine followed by allogeneic hematopoietic cell transplantation offer effective therapy for AML. We anticipated that pharmacokinetic targeting of i.v. BU to 5300 μm/L min/day × 4 (targeted i.v. BU and fludarabine (t-i.v. BU/Flu)) would limit nonrelapse mortality (...

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Publicat a:Bone Marrow Transplant
Autors principals: Pidala, J, Kim, J, Anasetti, C, Kharfan-Dabaja, MA, Field, T, Perkins, J, Ayala, E, Perez, L, Fernandez, H
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726256/
https://ncbi.nlm.nih.gov/pubmed/20711242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2010.190
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