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Delineation of the Exact Transcription Termination Signal for Type 3 Polymerase III

Type 3 Pol III promoters such as U6 are widely used for expression of small RNAs, including short hairpin RNA for RNAi applications and guide RNA in CRISPR genome-editing platforms. RNA polymerase III uses a T-stretch as termination signal, but the exact properties have not been thoroughly investiga...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther Nucleic Acids
Egile Nagusiak: Gao, Zongliang, Herrera-Carrillo, Elena, Berkhout, Ben
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725217/
https://ncbi.nlm.nih.gov/pubmed/29499947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.11.006
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