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Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia

PURPOSE: African Americans have a higher incidence and mortality from colorectal cancer. This disparity might be due, in part, to the type of mutations in driver genes. In this study, we examined alterations specific to APC, MSH3, and MSH6 genes using targeted exome sequencing to determine distincti...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ashktorab, Hassan, Azimi, Hamed, Varma, Sudhir, Tavakoli, Payaam, Nickerson, Michael L., Brim, Hassan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725144/
https://ncbi.nlm.nih.gov/pubmed/29245953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21557
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