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Driver genes exome sequencing reveals distinct variants in African Americans with colorectal neoplasia

BACKGROUND: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in the United States. African Americans are disproportionately affected by CRC. Our hypothesis is that driver genes with known and novel mutations have an impact on CRC outcome in this population. Therefore, we i...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ashktorab, Hassan, Azimi, Hamed, Varma, Sudhir, Lee, Edward L., Laiyemo, Adeyinka O., Nickerson, Michael L., Brim, Hassan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498998/
https://ncbi.nlm.nih.gov/pubmed/31080553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26721
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