Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia

PURPOSE: African Americans have a higher incidence and mortality from colorectal cancer. This disparity might be due, in part, to the type of mutations in driver genes. In this study, we examined alterations specific to APC, MSH3, and MSH6 genes using targeted exome sequencing to determine distincti...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Ashktorab, Hassan, Azimi, Hamed, Varma, Sudhir, Tavakoli, Payaam, Nickerson, Michael L., Brim, Hassan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725144/
https://ncbi.nlm.nih.gov/pubmed/29245953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21557
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