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The aldehyde group of gossypol induces mitochondrial apoptosis via ROS-SIRT1-p53-PUMA pathway in male germline stem cell

As a widely grown economic crop, cotton is the major oil and protein resource for human and livestock. But the highly toxic of gossypol in cottonseed severely restricts its effective utilization, consequently creating huge resource waste. Previous studies have shown the male germline stem cells were...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: He, Xin, Wu, Chongyang, Cui, Yanhua, Zhu, Haijing, Gao, Zhiming, Li, Bo, Hua, Jinlian, Zhao, Baoyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725007/
https://ncbi.nlm.nih.gov/pubmed/29245965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22044
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