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The aldehyde group of gossypol induces mitochondrial apoptosis via ROS-SIRT1-p53-PUMA pathway in male germline stem cell

As a widely grown economic crop, cotton is the major oil and protein resource for human and livestock. But the highly toxic of gossypol in cottonseed severely restricts its effective utilization, consequently creating huge resource waste. Previous studies have shown the male germline stem cells were...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: He, Xin, Wu, Chongyang, Cui, Yanhua, Zhu, Haijing, Gao, Zhiming, Li, Bo, Hua, Jinlian, Zhao, Baoyu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725007/
https://ncbi.nlm.nih.gov/pubmed/29245965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22044
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