Glipizide sensitizes lung cancer cells to TRAIL-induced apoptosis via Akt/mTOR/autophagy pathways

The combination of tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) with subsidiary agents is a promising anticancer strategy to conquer TRAIL resistance in malignant cells. Glipizide is a second-generation oral hypoglycemic medicine for the cure of type II diabetes because of its cap...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Nazim, Uddin MD., Moon, Ji-Hong, Lee, You-Jin, Seol, Jae-Won, Kim, Yong Ju, Park, Sang-Youel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724999/
https://ncbi.nlm.nih.gov/pubmed/29245957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21754
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