Enhancement of TRAIL-induced apoptosis by 5-fluorouracil requires activating Bax and p53 pathways in TRAIL-resistant lung cancers

Lung cancer, especially lung adenocarcinoma, is one of the main causes of death worldwide. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a primary anticancer agent and a member of the tumor necrosis factor family that selectively induces apoptosis in various tumor cells, but not...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Nazim, Uddin MD., Rasheduzzaman, Mohammad, Lee, You-Jin, Seol, Dai-Wu, Park, Sang-Youel
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392310/
https://ncbi.nlm.nih.gov/pubmed/28178647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14994
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