RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production

Follicular T helper cells (T(FH)) are fundamental in orchestrating effective antibody-mediated responses critical for immunity against viral infections and effective vaccines. However, it is unclear how virus infection leads to T(FH) induction. We here show that dengue virus (DENV) infection of huma...

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發表在:PLoS Pathog
Main Authors: Sprokholt, Joris K., Kaptein, Tanja M., van Hamme, John L., Overmars, Ronald J., Gringhuis, Sonja I., Geijtenbeek, Teunis B. H.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724900/
https://ncbi.nlm.nih.gov/pubmed/29186193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006738
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