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RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production

Follicular T helper cells (T(FH)) are fundamental in orchestrating effective antibody-mediated responses critical for immunity against viral infections and effective vaccines. However, it is unclear how virus infection leads to T(FH) induction. We here show that dengue virus (DENV) infection of huma...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Sprokholt, Joris K., Kaptein, Tanja M., van Hamme, John L., Overmars, Ronald J., Gringhuis, Sonja I., Geijtenbeek, Teunis B. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724900/
https://ncbi.nlm.nih.gov/pubmed/29186193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006738
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