Radiolabeling and initial biological evaluation of [(18)F]KBM-1 for imaging RAR-α receptors in neuroblastoma

Retinoic acid receptor alpha (RAR-α) plays a significant role in a number of diseases, including neuroblastoma. Children diagnosed with high-risk neuroblastoma are treated 13-cis-retinoic acid, which reduces risk of cancer recurrence. Neuroblastoma cell death is mediated via RAR-α, and expression of...

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Detaylı Bibliyografya
Yayımlandı:Bioorg Med Chem Lett
Asıl Yazarlar: Sai, Kiran Kumar Solingapuram, Das, Bhaskar C., Sattiraju, Anirudh, Almaguel, Frankis G., Craft, Suzanne, Mintz, Akiva
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724519/
https://ncbi.nlm.nih.gov/pubmed/28216044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.01.093
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