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Functional assessment of CYP3A4 allelic variants on lidocaine metabolism in vitro
AIM: Human cytochrome P450 3A4 is the most abundant isoform of P450 enzyme in the liver. It plays an important role in the metabolism of wide variety of xenobiotic and endogenous substrates. So far, there are few reports about the functional characterization of CYP3A4 variants in terms of specific s...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5724423/ https://ncbi.nlm.nih.gov/pubmed/29263648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S152366 |
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