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Chemical probes and engineered constructs reveal a detailed unfolding mechanism for a solvent-free multi-domain protein
Despite the growing application of gas-phase measurements in structural biology and drug discovery, the factors that govern protein stabilities and structures in a solvent-free environment are still poorly understood. Here, we examine the solvent-free unfolding pathway for a group of homologous seru...
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| Udgivet i: | J Am Chem Soc |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5724362/ https://ncbi.nlm.nih.gov/pubmed/27959526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11678 |
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