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A simple method for probing the mechanical unfolding pathway of proteins in detail

Atomic force microscopy is an exciting new single-molecule technique to add to the toolbox of protein (un)folding methods. However, detailed analysis of the unfolding of proteins on application of force has, to date, relied on protein molecular dynamics simulations or a qualitative interpretation of...

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Detalhes bibliográficos
Main Authors: Best, Robert B., Fowler, Susan B., Toca-Herrera, José L., Clarke, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129412/
https://ncbi.nlm.nih.gov/pubmed/12218181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192351899
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