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Development of novel biosensors to study receptor-mediated activation of the G-protein α subunits G(s) and G(olf)

Gα(s) (G(s)) and Gα(olf) (G(olf)) are highly homologous G-protein α subunits that activate adenylate cyclase, thereby serving as crucial mediators of intracellular signaling. Because of their dramatically different brain expression patterns, we studied similarities and differences between their acti...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yano, Hideaki, Provasi, Davide, Cai, Ning Sheng, Filizola, Marta, Ferré, Sergi, Javitch, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723988/
https://ncbi.nlm.nih.gov/pubmed/29042444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.800698
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