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Putative Active States of a Prototypic G-Protein-Coupled Receptor from Biased Molecular Dynamics
A major current focus of structural work on G-protein-coupled receptors (GPCRs) pertains to the investigation of their active states. However, for virtually all GPCRs, active agonist-bound intermediate states have been difficult to characterize experimentally owing to their higher conformational fle...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872269/ https://ncbi.nlm.nih.gov/pubmed/20483344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.047 |
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