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Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation
Meningiomas frequently display activation of the PI3K/AKT/mTOR pathway, leading to elevated levels of phospho-4E binding proteins, which enhances protein synthesis; however, it is not known whether inhibition of protein translation is an effective treatment option for meningiomas. We found that huma...
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| 出版年: | Exp Neurol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5723558/ https://ncbi.nlm.nih.gov/pubmed/28610844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2017.06.015 |
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