Radiation-enhanced delivery of systemically administered amphiphilic-CpG oligodeoxynucleotide

Along with vaccines and checkpoint blockade, immune adjuvants may have an important role in tumor immunotherapy. Oligodeoxynucleotides containing unmethylated cytidyl guanosyl dinucleotide motifs (CpG ODN) are TLR9 ligands with attractive immunostimulatory properties, but intratumoral administration...

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Bibliografske podrobnosti
izdano v:J Control Release
Main Authors: Appelbe, Oliver K., Moynihan, Kelly D., Flor, Amy, Rymut, Nick, Irvine, Darrell J., Kron, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723529/
https://ncbi.nlm.nih.gov/pubmed/28987882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.09.043
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