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Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2-deficient mice
Alterations in the balance between neuronal excitation and inhibition (E:I balance) have been implicated in the neural circuit activity–based processes that contribute to autism phenotypes. We investigated whether acutely reducing E:I balance in mouse brain could correct deficits in social behavior....
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| Publicado no: | Sci Transl Med |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5723386/ https://ncbi.nlm.nih.gov/pubmed/28768803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aah6733 |
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