Zinc deficiency as a codeterminant for airway epithelial barrier dysfunction in an ex vivo model of COPD

There is now convincing evidence that the airway epithelium drives the pathogenesis of COPD. A major aspect of this is the disease-related reduction in barrier function that is potentiated by dysregulation of tight junction (TJ) protein complexes. However, a significant number of studies using in vi...

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Vydáno v:Int J Chron Obstruct Pulmon Dis
Hlavní autoři: Roscioli, Eugene, Jersmann, Hubertus PA, Lester, Susan, Badiei, Arash, Fon, Andrew, Zalewski, Peter, Hodge, Sandra
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723110/
https://ncbi.nlm.nih.gov/pubmed/29255357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S149589
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