Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling

BACKGROUND: Transforming growth factor beta (TGFB) superfamily signaling is implicated in the development of sex cord-stromal tumors, a category of poorly defined gonadal tumors. The aim of this study was to determine potential effects of dysregulated TGFB signaling in the ovary using Cre recombinas...

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Bibliographic Details
Published in:Reprod Biol Endocrinol
Main Authors: Gao, Yang, Fang, Xin, Vincent, David F., Threadgill, David W., Bartholin, Laurent, Li, Qinglei
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723096/
https://ncbi.nlm.nih.gov/pubmed/29221447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-017-0312-z
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