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Long-term maintenance of peripheral blood derived human NK cells in a novel human IL-15- transgenic NOG mouse
We generated a novel mouse strain expressing transgenic human interleukin-15 (IL-15) using the severe immunodeficient NOD/Shi-scid-IL-2Rγ(null) (NOG) mouse genetic background (NOG-IL-15 Tg). Human natural killer (NK) cells, purified from the peripheral blood (hu-PB-NK) of normal healthy donors, prol...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5722902/ https://ncbi.nlm.nih.gov/pubmed/29222435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17442-7 |
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