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Vaccine-elicited memory CD4(+) T cell expansion is impaired in the lungs during tuberculosis
Immunological memory is the key biological process that makes vaccines possible. Although tuberculosis vaccines elicit protective immunity in animals, few provide durable protection. To understand why protection is transient, we evaluated the ability of memory CD4(+) T cells to expand, differentiate...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5720822/ https://ncbi.nlm.nih.gov/pubmed/29176787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006704 |
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