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TCR-Engineered, Customized, Antitumor T Cells for Cancer Immunotherapy: Advantages and Limitations

The clinical outcome of the traditional adoptive cancer immunotherapy approaches involving the administration of donor-derived immune effectors, expanded ex vivo, has not met expectations. This could be attributed, in part, to the lack of sufficient high-avidity antitumor T-cell precursors in most c...

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Detalhes bibliográficos
Publicado no:ScientificWorldJournal
Autor principal: Chhabra, Arvind
Formato: Artigo
Idioma:Inglês
Publicado em: TheScientificWorldJOURNAL 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720046/
https://ncbi.nlm.nih.gov/pubmed/21218269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2011.10
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