PLAC1-specific TCR-engineered T cells mediate antigen-specific antitumor effects in breast cancer

Placenta-specific 1 (PLAC1), a novel cancer-testis antigen (CTA), is expressed in a number of different human malignancies. It is frequently produced in breast cancer, serving a function in tumorigenesis. Adoptive immunotherapy using T cell receptor (TCR)-engineered T cells against CTA mediates obje...

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Veröffentlicht in:Oncol Lett
Hauptverfasser: Li, Qiongshu, Liu, Muyun, Wu, Man, Zhou, Xin, Wang, Shaobin, Hu, Yuan, Wang, Youfu, He, Yixin, Zeng, Xiaoping, Chen, Junhui, Liu, Qubo, Xiao, Dong, Hu, Xiang, Liu, Weibin
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844056/
https://ncbi.nlm.nih.gov/pubmed/29556312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8075
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