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The Origins, Specificity, and Potential Biological Relevance of Human Anti-IgG Hinge Autoantibodies

Human anti-IgG hinge (HAH) autoantibodies constitute a class of immunoglobulins that recognize cryptic epitopes in the hinge region of antibodies exposed after proteolytic cleavage, but do not bind to the intact IgG counterpart. Detailed molecular characterizations of HAH autoantibodies suggest that...

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Detalhes bibliográficos
Publicado no:ScientificWorldJournal
Main Authors: Brezski, Randall J., Knight, David M., Jordan, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: TheScientificWorldJOURNAL 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720009/
https://ncbi.nlm.nih.gov/pubmed/21623461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2011.107
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