Sublingual targeting of STING with 3′3′-cGAMP promotes systemic and mucosal immunity against anthrax toxins

Anthrax is caused by Bacillus anthracis, a zoonotic bacterial pathogen affecting humans and livestock worldwide. The current human anthrax vaccine, anthrax vaccine adsorbed (AVA), is an injected vaccine with a cumbersome administration schedule and fails to promote mucosal immunity. Bacterial entero...

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Vydáno v:Vaccine
Hlavní autoři: Martin, Tara L., Jee, Junbae, Kim, Eunsoo, Steiner, Haley E., Cormet-Boyaka, Estelle, Boyaka, Prosper N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719503/
https://ncbi.nlm.nih.gov/pubmed/28343781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.02.064
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