Neutrophils negatively regulate induction of mucosal IgA responses after sublingual immunization

Induction of mucosal IgA capable of providing a first line of defense against bacterial and viral pathogens remains a major goal of needle-free vaccines given via mucosal routes. Innate immune cells are known to play a central role in induction of IgA responses by mucosal vaccines, but the relative...

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Udgivet i:Mucosal Immunol
Main Authors: Jee, Junbae, Bonnegarde-Bernard, Astrid, Duverger, Alexandra, Iwakura, Yoichiro, Cormet-Boyaka, Estelle, Martin, Tara L., Steiner, Haley E., Bachman, Ryan C., Boyaka, Prosper N.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481173/
https://ncbi.nlm.nih.gov/pubmed/25563500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.105
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